It last sold at Sotheby's in 2004 for $16.8 million.
The work had been in a private Midwestern collection for more than four decades.
The work once hung in Adolf Hitler's Reich Chancellery.
One of artist's final few works is coming to market again after seven years of being held privately.
As the vaccine rollout continues apace in the U.K., buyers are growing more active.
More than half of the oil studies for Seurat's most famous paintings are held by museums.
Works Paul Cézanne, Edgar Degas and Claude Monet, all from the same private collection, will take center stage.
They will be auctioned alongside a statue of a Tibetan deity.
Six years since a record price was set for a Mondrian, Christie's brings another classic painting to market.
Works from their private collection are expected to sell for $4.6 million at Christie's.